DNA Mechanics

We use AFM and computational approaches to investigate the elasticity of single-stranded DNA and force-induced conformational transitions in ssDNA.

Selected Publications:

• Origin of overstretching transition in single-stranded DNA PRL, 2013.
• Detecting solvent-driven transitions of poly(A) to double-stranded conformations by atomic force microscopy Biophys. J., 2009.
• Direct measurements of base-stacking PRL, 2007.